The age symptoms begin and severity of symptoms can vary depending on how much working alpha-1 antitrypsin protein (AAT) a person has. Lung (pulmonary) problems almost always occur in adults, whereas liver and skin problems may occur in adults and children. Listen Alpha-1 antitrypsin deficiency (AATD) is an inherited disease that causes an increased risk of having chronic obstructive pulmonary disease (COPD), liver disease, skin problems ( panniculitis), and inflammation of the blood vessels ( vasculitis). Table of Contents expand submenu for Table of Contents.Preguntas Más Frecuentes Sobre los Trastornos Cromosómicos.Consejos Para Obtener Ayuda Financiera Para Una Enfermedad.Consejos Para una Condición no Diagnosticada.Como Encontrar un Especialista en su Enfermedad.Preguntas Más Frecuentes Sobre Enfermedades Raras.Guías de Información expand submenu for Guías de Información.En Español expand submenu for En Español.About GARD expand submenu for About GARD.Teachers and Students expand submenu for Teachers and Students.Researchers expand submenu for Researchers.Caring for Your Patient with a Rare Disease.Healthcare Professionals expand submenu for Healthcare Professionals.

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Lost alpha lab x18